Week 2 Midterm Exam: NR546 / NR-
546 (Latest 2025 / 2026) Advanced Pharmacology Psychopharmacology for the PMHNP | Questions and Answers | 100% Correct | Grade A - Chamberlain
Question:
What influences drug metabolism
Answer:
age, smoking, caffeine, other mediation/polypharmacy, nicotine
Question:
How are medication effected with poor metabolizers
Answer:
poor metabolizers have lower concentrations of the enzymes needed to metabolize drugs. Therefore, they would have higher blood concentration, elevated drug levels and increased risk of drug-drug reaction, risk for drug toxicity
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Question:
How are medication effected with rapid metabolizers
Answer:
elevated enzyme activity breaks the drug down faster and causes subtherapeutic drug levels- need higher doses for drug to be effective •
Question:
Most drug doses are set at values for what type of metabolizer
Answer:
extensive
Question:
Signal transduction cascades
Answer:
Signal transduction cascades can produce downstream (delayed) and/or long- lasting effects, which explains why some psychopharmacological drugs do not provide an immediate response but require time to see the drug effects.
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Question:
How are drug blood concentration affected with poor metabolizers
Answer:
Poor metabolizers have a lower concentration of the necessary enzyme which results in higher blood concentrations of the drug.
Question:
g-linked protein
Answer:
Is triggered by a NTM. Passes messages from one receptor to another. the second messenger is a chemical; once bound to enzyme it changes shape
Question:
most comon inhibitory NTM in the spinal cord
Answer:
glycine
Question:
What is the theory of how psychotropic medication work
Answer:
psychotropic mediation impact NTM by either enhancing or decreasing the NTM ability to bind to receptor sites
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