USMLE Step 1 Rapid Review
abdominal pain, ascites, hepatomegaly (Ans- Budd-Chiari syndrome
Familial hypercholesterolemia (Ans- achilles tendon xanthoma
adrenal hemorrhage, hypotension, DIC (Ans- Waterhouse-Friderichsen syndrome
biochemistry of Marfan's syndrome (Ans- fibrillin defect
posthepatic venous thrombosis (Ans- Budd-Chiari syndrome
Familial hypercholesterolemia biochemistry (Ans- decrease in LDL receptor signaling
Waterhouse-Friderichsen syndrome cause (Ans- meningococcemia
arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints (Ans- Marfan's syndrome
Athlete with polycythemia (Ans- EPO injection
Pott's disease (Ans- vertebral TB
Pott's disease clinical presentation (Ans- back pain, fever, night sweats, weight loss 1 / 4
Sarcoidosis main histological presentation (Ans- noncaseating granuloma
bilateral hilar adenopathy + uveitis (Ans- sarcoidosis
Osteogenesis imperfecta (Ans- type I collagen defect
Blue sclera indicate what?(Ans- osteogenesis imperfecta
Burton's line indicates what?(Ans- lead poisoning
Burton's line (Ans- bluish line on gingiva
Paget's disease of the bone biochemistry (Ans- increase in osteoblastic and osteoclastic activity
bone pain, bone enlargement, arthritis (Ans- Paget's disease of the bone
bounding pulses, diastolic heart murmur, head bobbing (Ans- aortic regurgitation
butterfly facial rash, Raynaud's phenomenon in a young female (Ans- SLE
Neurofibromatosis type I associated with what malignancies (Ans- pheochromocytoma, optic gliomas
- / 4
cafe-au-lait spots and Lisch nodules (Ans- Neurofibromatosis type I
Lisch nodules (Ans- iris hemartoma
McCune-Albright syndrome biochemistry (Ans- mosaic continuous activation of stimulatory G protein
cafe-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities (Ans- McCune-Albright syndrome
Duchenne's muscular dystrophy (Ans- X-linked recessive deletion of dystrophin gene
Calf pseudohypertrophy (Ans- Duchenne's muscular dystrophy
clinical sign of Tay-Sach's, Niemann-Pick, or central retinal artery occlusion (Ans- Cherry-red spot on macula
ganglioside accumulation (Ans- Tay-Sach's
sphingomyelin accumulation (Ans- Niemann-Pick disease
Stable angina (Ans- with moderate exercise
Unstable angina (Ans- with minimal exertion
- / 4
Angina (Ans- chest pain on exertion
autoimmune-mediated post-MI fibrinous pericarditis 1-12 weeks after acute episode (Ans- Dressler syndrome
Chest pain, pericardial effusion, friction rub, persistent fever following MI 1- 12 weeks after (Ans- Dressler's syndrome
Gowers' sign associated with what disease?(Ans- Duchenne muscular dystrophy
Gower's sign definition (Ans- child uses arms to stand up from squat
"Slapped cheeks" (Ans- erythema infectiosum/fifth disease
Erythema infectiosum/fifth disease (Ans- parvovirus B19
child with fever later develops red rash on face that spreads to body (Ans- erythema infectiosum/fifth disease
autosomal-dominant CAG repeat expansion (Ans- Huntington's disease
chorea, dementia, caudate degeneration (Ans- Huntington's disease
muscle glycogen phosphorylase deficiency (Ans- McArdle's syndrome
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