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UPDATED ONS ONCC CHEMO
RENEWAL QUESTIONS AN D
ANSWERS100% VERIFIED AND
GRADED A+
Question 1: What is the main benefit of neoadjuvant
chemotherapy for a breast cancer patient?
CORRECT ANSWER : It can change surgical options if
the tumor is shrunk enough, potentially allowing for a lumpectomy plus radiation therapy instead of a mastectomy.
Question 2: Due to Mrs. Turner's age and comorbidities,
her oncologist performs a comprehensive geriatric assessment. You know that this assessment covers all but which of the following?
CORRECT ANSWER : The assessment includes
functional status, socioeconomic issues, psychosocial distress, comorbidities, cognitive function, nutritional status, polypharmacy, and a medication review.
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Question 3: According to the NCCN Older Adult
Oncology Guidelines (version 1.2015), more than 60% of cancers in the United States occur in people age ______ and older.
CORRECT ANSWER : 65
Question 4: What is your best explanation for why Mrs.
Turner was given a port to receive her chemotherapy?
CORRECT ANSWER : Two of the agents (docetaxel
and carboplatin) are categorized as irritants, and docetaxel can cause a significant reaction if it extravasates, leading to edema, erythema, occasional pain, and blister formation. A port reduces the risk of such complications.
Question 5: What are irritants in the context of
chemotherapy?
CORRECT ANSWER : Irritants can cause inflammation,
pain, and burning but rarely cause tissue necrosis comparable to a vesicant, unless a large amount or a very high concentration is extravasated.
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Question 6: What are vesicants in the context of
chemotherapy?
CORRECT ANSWER : Vesicants can cause blistering
and significant pain and tissue damage and destruction, leading to tissue death.
Question 7: How are antineoplastic agents further
classified based on their potential to cause damage?
CORRECT ANSWER : A further classification of an
antineoplastic agent's potential to cause damage is whether its mechanism of action includes DNA binding.Non-DNA-binding solutions remain in the local area of extravasation, improving the possibility of drug deactivation, while DNA-binding agents attach to DNA nucleic acids, causing progressive tissue destruction.
Question 8: Which agents are classified as DNA-binding
irritants?
CORRECT ANSWER : Bendamustine, Dactinomycin,
Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Mechlorethamine, Mitomycin.
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Question 9: Which agents are classified as DNA non-
binding vesicants?
CORRECT ANSWER : Amsacrine, Paclitaxel,
Vinblastine, Vincristine, Vindesine, Vinorelbine.
Question 10: What is the treatment for extravasation of
mechlorethamine (alkylating agent)?
CORRECT ANSWER : Inject 2 ml of sodium thiosulfate
for each milligram of mechlorethamine extravasated, subcutaneously into the extravasation site using a 25- gauge or smaller needle, changing the needle with each injection, and monitor per institutional policies.
Question 11: What is the treatment for extravasation of
oxaliplatin (alkylating agent)?
CORRECT ANSWER : Apply warm compresses and
administer dexamethasone 8 mg twice daily for 14 days.