PTRS 855 Module 12 (Neurological Pharmacology) Questions With Complete Solutions Parkinson's disease - Correct Answers ✅Disease that requires drugs in order to increase dopamine levels in the basal ganglia Carbidopa, Sinemet - Correct Answers ✅For the treatment of Parkinson's disease, levodopa is usually paired with ? to prevent the conversion of levodopa until it reaches the brain; this drug combination is known by the trade name ?Dyskinesias (treated with apomorphine) - Correct Answers ✅Most difficult symptom of levodopa Etilevodopa, melevodopa - Correct Answers ✅Methyl and ethyl-esterified forms of levodopa that should allow the drug to cross the BBB before being broken down Amantadine - Correct Answers ✅Drug for Parkinson's that is usually given along with levodopa to facilitate the release of endogenous dopamine Anticholinergic drugs - Correct Answers ✅Drugs that decrease acetylcholine levels to balance the dopamine/acetylcholine ratio in an attempt to reduce symptoms such as tremors and rigidity 1 / 2
PTRS 855 Module 12 (Neurological Pharmacology) Questions With Complete Solutions Trihexyphenidyl, benzotropine - Correct Answers ✅Two generic drug names for anticholinergic drugs Anticholinergic drugs - Correct Answers ✅Side effects for
this type of drugs include:
- Memory impairment
- Hallucinations
- Dry mouth
- Constipation
- Urinary retention
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Antioxidants - Correct Answers ✅Type of drugs used to treat Parkinson's that lower the body's concentration of free radicals; may slow the progression of the disease rather than just treating symptoms Selegiline, rasagiline - Correct Answers ✅Two generic drug names for antioxidant drugs GM-1 ganglioside - Correct Answers ✅Drug for Parkinson's that is made of a component of the neuronal membrane that helps maintain membrane integrity which allows the drug to prevent neuronal damage