WGU D027
PATHOPHARMACOLOGICAL
ADVANCED FOUNDATIONS EXAM
QUESTIONS WITH CORRECT
ANSWERS 100%
Question : What are some physical changes from Alzheimer's
dementia?
CORRECT ANSWER : - Brain shrinks dramatically; nerve
cell death and tissue loss - Cardinal signs: plaques (abnormal
clusters of protein fragments) and tangles (twisted strands of another protein)
Question : How is Alzheimer's treated?
CORRECT ANSWER : - There is no cure, but there are
pharmacological and non-pharmacological treatments - Cholinesterase inhibitors - Memantine (namenda)
Question : What are cholinesterase inhibitors prescribed for?
CORRECT ANSWER: - To treat symptoms related to
memory, thinking, language, judgment, and other processes - Helps delay or slow the worsening of symptoms
Question : What does cholinesterase inhibitors do?
CORRECT ANSWER : - Prevent the breakdown of
acetylcholine, a chemical messenger that is important for learning and memory - Supports communication among nerve cells by keeping the acetylcholine high
Question : What are some commonly prescribed
cholinesterase inhibitors?
CORRECT ANSWER : - Donepezil (aricept) - Galantamine
(razadyne) - Rivastigmine (exeleon)
Question : Which cholinesterase inhibitor can be used for all
stages of Alzheimer's?
CORRECT ANSWER : - Donepezil (aricept)
Question : Which cholinesterase inhibitor can be used for
mild-to-moderate stages of Alzheimer's?
CORRECT ANSWER : - Galantamine (razadyne) -
Rivastigmine (exeleon)
Question : Which cholinesterase inhibitor can be used for
mild-to-moderate Alzheimer's and Parkinson's?
CORRECT ANSWER : - Rivastigmine (exeleon)
Question : What medication combination is used to treat
moderate-to-severe Alzheimer's?
CORRECT ANSWER : - Memantine (namenda) and
donepezil (aricept)
Question : What is memantine (namenda) used for?
CORRECT ANSWER : - Prescribed to improve memory,
attention, reason, language, and the ability to perform simple tasks - Can be used alone or with other Alzheimer's disease treatments
Question : How does memantine (namenda) work?
CORRECT ANSWER : - Regulates the activity of glutamate,
a chemical involved in information processing, storage, and retrieval - Improves mental functioning and ability to perform daily activities for some people
Question : What is the difference in MOA between
cholinesterase inhibitors and memantine (namenda)?
CORRECT ANSWER : - Cholinesterase inhibitors prevent
the breakdown of acetylcholine, whereas memantine (namenda) regulates the activity of glutamate
Question : What is ataxia?
CORRECT ANSWER : - Also known as cerebellum attacks
- Degenerative disease of the nervous system - Many
symptoms mimic those of being drunk (i.e. slurred speech, stumbling, falling, and incoordination)
Question : What causes the symptoms of ataxia?
CORRECT ANSWER : - The damage caused to the
cerebellum, the part of the brain that is responsible for