ONS ONCC Chemo Renewal Exam Latest Version Questions and Verified Accurate Correct Answers Guaranteed A+ 8.4% - Correct Answer It is important that the nurse recognizes certain drugs that, when given together, may result in a higher risk of adverse events. For example, in neoadjuvant clinical trials using trastuzumab and pertuzumab, the incidence of decline in left ventricular ejection fraction (LVEF) was 1.9% in patients treated with trastuzumab and docetaxel, compared to ______ of those treated with trastuzumab, docetaxel, and pertuzumab (Genentech, 2013).
50 - Correct Answer The chance of developing colorectal cancer increases markedly after age _____. Roughly 9 out of 10 people diagnosed with colorectal cancer are at least ____ years old.
65 - Correct Answer The NCCN Older Adult Oncology Guidelines (version 1.2015) provides information on what is included in a comprehensive geriatric assessment.Currently, more than 60% of cancers in the United States occur in people age ______and older and as the oncology world ages, nearly half (46%) of cancer survivors are 70 years of age or older
85% - Correct Answer Amgen (2007) defines RDI as "is a quantification of how closely an administered course of chemotherapy treatment adheres to a specific regimen." Three separate clinical trials evaluating outcomes in patients with breast cancer related to RDI have demonstrated improved overall survival and 10-year disease free survival in patients who receive a RDI > or = ____?_____
A comprehensive geriatric assessment (CGA) is a multidisciplinary evaluation to assess life expectancy and risk of morbidity and mortality in the older patient. This assessment tool would evaluate and include the following areas: functional status, socioeconomic issues, psychosocial distress, comorbidities, cognitive function, nutritional status, polypharmacy, and a medication review (NCCN Older Adult Oncology Guidelines, version 1.2015). - Correct Answer Due to Mrs. Turner's age and comorbidities, her oncologist performs a comprehensive geriatric assessment. You
know that this assessment covers all but which of the following:
A dose-limiting toxicity of cyclophosphamide is hemorrhagic cystitis. Although it is more commonly seen with high-dose therapy, it can still occur in patients receiving R-CHOP. - Correct Answer Which of the agents that Mr. Rylan is receiving in R-CHOP would be the likely culprit if this is hemorrhagic cystitis?
- Stop the paclitaxel infusion - Correct Answer Mrs. Kearns is receiving her first dose
of paclitaxel and about 20 minutes into the infusion, you notice that she begins to start clearing her throat a lot. She also states that she is having some lower back pain. You decide that you will take another set of vital signs. While you are waiting for the monitor 1 / 2
to reveal her blood pressure, she begins to breathe heavier and appears short of breath.
What is the first/immediate thing you need to do for Mrs. Kearns?
Administering HDs by any route (PO, IV, IT, etc.) Handling any HD vials, ampules, or packaging materials Introducing or withdrawing needles or dispensing pins from HD vials TrCorrect Answerferring drugs from HD vials to other containers using needles, dispensing pins, or syringes Opening ampules or HDs Expelling air from an HD-filled syringe Spiking IV bags containing HDs and changing IV tubing Priming IV tubing with HDs Handling HD leakage from tubing, syringe, and connection sites Discontinuing infusions of HDs Disposing of HDs and items contaminated by HDs Handling the body fluids of a patient who had received HDs in the past 48 hours Cleaning HD spills Touching any surface that is potentially contaminated with HD residue - Correct Answer PPE should be worn whenever there is a potential that hazardous drugs could be
released into the environment like in the following situations:
Although all the other Correct Answerwers listed can happen with rituximab, you are most concerned about the potential for a hypersensitivity reaction since this is rituximab and it is the patient's first dose. - Correct Answer What is the most important toxicity that you will monitor for with rituximab especially since this is the patient's first dose of the agent?
Although hypersensitivity and infusion reactions can occur at any time and potentially with any chemotherapy agent, there are certain agents that have a higher risk of causing a reaction. For some agents, the reaction is more likely to occur after they have received a few doses and have already been exposed to the same agent. On the other hand, there are agents where the hypersensitivity reactions can occur almost immediately on exposure. Reactions to platinum drugs (e.g., carboplatin, cisplatin, oxaliplatin) usually occur after multiple treatments. However, reactions caused by taxanes (e.g., paclitaxel, docetaxel) usually occur within the first hour of the first or second treatment. Reactions to monoclonal antibodies like rituximab and cetuximab usually occur with the first treatment as well. (Information from Zetka article) - Correct Answer Which of the following agents would you anticipate a hypersensitivity reaction more often occurring after the patient has already received several doses?
Amsacrine Paclitaxel Vinblastine Vincristine
- / 2