NUR 600 - Final Exam Advanced Clinical Pharmacology Latest Update 2025-2026 Exam 75 Questions with 100% Verified Correct Answers Guaranteed A+
Aricept (donepezil) - CORRECT ANSWER: Alzheimer's disease
Aricept dosing - CORRECT ANSWER: The recommended starting dosage of ARICEPT
is 5 mg administered once per day in the evening, just prior to retiring. My be increased after 4-6 weeks with the maximum recommended dosage of ARICEPT in patients with mild to moderate Alzheimer's disease is 10 mg per day. Improvement 3-6 weeks after initiation.
Aricept indication - CORRECT ANSWER: Alzheimer's dementia
Aricept mechanism of action - CORRECT ANSWER: Inhibits centrally active
acetylcholinesterase
Bacterial Vaginosis (BV) - CORRECT ANSWER: a condition in women in which there is an abnormal overgrowth of certain bacteria in the vagina
Contraindications - CORRECT ANSWER: ARICEPT is contraindicated in patients with
known hypersensitivity to donepezil hydrochloride or to piperidine derivatives.ARICEPT, as a cholinesterase inhibitor, is likely to exaggerate succinylcholine-type muscle relaxation during anesthesia
Contraindications - CORRECT ANSWER: hormone problems; asthma; emphysema;
mental illness; diabetes; stomach ulcers; heart attacks; an irregular heartbeat; or blood vessel, heart, kidney, liver or lung disease
contraindications - CORRECT ANSWER: VPA is contraindicated in patients with
significant hepatic impairment, hypersensitivity to components of the drug or its class, urea cycle disorders, mitochondrial disorders, suspected disorders in patients younger than 2, and during pregnancy, especially for migraine prophylaxis with VPA
contraindications of dilantin - CORRECT ANSWER: None other than allergy - Dilantin is contraindicated in those patients with a history of hypersensitivity to phenytoin, its inactive ingredients, or other hydantoins.
contraindications of phenobarb - CORRECT ANSWER: Phenobarbital is contraindicated in patients with sever liver disease known barbiturate sensitivity. Barbiturates, including 1 / 2
phenobarbital, are contraindicated in a patient with a history/manifest or latent porphyria, liver impairment, and large doses in patients with nephritic syndrome.
contraindications of sumatriptan - CORRECT ANSWER: Sumatriptan also is
contraindicated in patients who use ergotamine and another 5-HT1 agonist concurrently. Patients with peripheral vascular disease (also, ischemic bowel disease), cerebrovascular syndromes, or uncontrolled hypertension have a contraindication to sumatriptan.
contraindications of tegretol - CORRECT ANSWER: Tegretol should not be used in
patients with a history of previous bone marrow depression, hypersensitivity to the drug, or known sensitivity to any of the tricyclic compounds, such as amitriptyline, desipramine, imipramine, protriptyline, nortriptyline, etc., pregnancy, heart failure and do not take with grapefruit
contraindications of topirimate - CORRECT ANSWER: have ever had an allergic
reaction to topiramate or any other medicine. have kidney problems, especially kidney stones. have a blood disorder called acute porphyria. have a history of blood metabolic acidosis, where the body produces too much acid or cannot remove it properly.
Dilantin (PHENYTOIN) - CORRECT ANSWER: Phenytoin
Anticonvulsant
dosage - CORRECT ANSWER: Adults - Indicated as monotherapy and adjunctive
therapy for complex partial seizures that occur either in isolation or in association with other types of seizures IV (valproate sodium): 10-15 mg/kg/day IV divided q12hr infused over 1 hr; maximum dose 60 mg/kg/day; do not exceed 14 days (switch to PO as soon as possible) PO: 10-15 mg/kg/day PO initially; increase by 5-10 mg/kg/day at weekly intervals; may increase dose up to 60 mg/kg/day
Children ndicated as monotherapy and adjunctive therapy for complex partial seizures that occur either in isolation or in association with other types of seizures
<10 years: Safety and efficacy not established
(IV) valproate sodium: 10-15 mg/kg/day IV divided q12hr infused over 1 hr; maximum dose 60 mg/kg/day; do not exceed 14 days (switch to PO as soon as possible) PO (Depakene or Stavzor): 10-15 mg/kg/day PO initially; increase by 5-10 mg/kg/day at weekly intervals; may increase dose up to 60 mg/kg/day
dosage for dilantin - CORRECT ANSWER: Status epilepticus
Load 15-20 mg/kg at 25-50 mg/min, THEN
Maintenance: 4-6 mg/kg/hour (adults and children)
Administer IV slowly; not to exceed 50 mg/min
Anticonvulsant
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