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NUR 521 ADV PHARM EXAM 1 Newest 2025 Complete Questions And Correct Answers (Verified Answers) |Already Graded A+||Brand New!!
What important teaching should be provided for the drug Cyclobenzaprine? What is serotonin syndrome? What is s/s?What is AE of this drug? - ANSWER-Cyclobenzaprine (Amrix)
Centrally Acting Muscle Relaxer - Work in brainstem to reduce tonic motor activity
Teaching: Fall risk, CNS depressant, S/S of serotonin syndrome
Serotonin Syndrome AE: AMS (agitation, restlessness,
confusion, hallucinations), Autonomic Nervous System (tachycardia, hyperthermia, diaphoresis, HTN, pupil dilation), Muscular Sx (tremor, hyperreflexia, ataxia, muscle twitching, rigidity)
AE: CNS depression, anticholinergic sx, dysrhythmias 1 / 4
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What is a contraindication of Dantrolene? BBW? - ANSWER- Dantrolene (Dantrium)
Direct Acting Muscle Relaxant
CI: Liver disease
BBW: Fatal Hepatotoxiticity
What is the BBW associated with Baclofen? What should the provider know about administration of this drug? - ANSWER- Baclofen (Lioresal)
Centrally Acting Muscle Relaxer
BBW: ABrupt withdrawal of intrathecal baclofen - high fever,
AMS, exaggerated rebound spasticity, muscle rigidity that can advance to MODS and rhabdo
Provider should know: 2 / 4
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Caution with other CNS depressants, history of BPH, psych conditions. Used to reduce spasticity.
We discussed two prototype drugs used to treat seizures.Compare and contrast these drugs. How do they work? What type of seizure do they treat? What precautions should be taken?What would you teach your patient? - ANSWER-Phentoin (Dilantin)
Traditional Drug Class
MOA: inhibition of Na channels resulting in decreased action
potentials
Treat partial and generalized tonic-clonic seizures (NOT absence seizures)
CI: HLA B1502 mutation, pregnancy, IV dose can cause
hypotension/dysrhythmias
Education: dont stop abruptly, seizure chart, plasma level
monitoring, folic acid during pregnancy, good oral hygiene 3 / 4
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Oxycarbazepine (Trileptal)
Newer Drug Class
MOA: block Na channels in neuronal membranes, stabilizing
hyper neurons
Treat partial seizures
-Hyponatremia can occur, especially with diuretics. SJS/TEN can occur.
-Same pt ed
**most important rule with antiseizure drugs is that they must be withdrawn slowly (6 weeks to several months)
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