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NSG 532 EXAM 4 PRACTICE
QUESTIONS WITH 100% CORRECT
ANSWERS
Question : Define Immunology
CORRECT ANSWER : The science of self (well ordered
host) and non-self (pathogens/disordered self) discrimination
Question : Define physiologic responses of the immune
system
CORRECT ANSWER : Proper self recognition
Effective immune responses Complete elimination Long lasting remembrance
Question : Define pathological responses of the immune
system
CORRECT ANSWER : Hyperactivity
-autoimmunity
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-hypersensitivity Hypoactivity -immune deficiencies -malignancies -infections
Question : Describe possible things that can be considered
"non-self"
CORRECT ANSWER : Obligatory intra/extracellular
microbes Facultative intracellular microbes Opportunistic microbes Transformed/mutated cells Diseased cells Aged/dead cells Infected/toxic cells Mismatched transplanted cells
Question : Define an epitope
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CORRECT ANSWER : The part of the antigen that is
specifically recognized by antibodies Also called an antigenic determinant ---meaning antibodies interaction with the antigen/epitope will determine the immune response
Question : What is the difference between an antigen and
immunogen?
CORRECT ANSWER : Both are types of epitopes
Antigen -Provokes weak/no immune response -Can react with immune response products -produces weak or no memory Immunogen -Provokes strong immune response -can react with immune response product -produces long-lasting memory
Question : What is a hapten?
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CORRECT ANSWER: A non-immunogenic epitope
When a hapten comes in contact with a carrier protein, the complex becomes immunogenic
Question : What criteria are immunogens judged upon?
CORRECT ANSWER : Degree of foreigness
Size/molecular weight Chemical nature/complexity Ability to degrade Dose Route of presentation
Question : What are the primary immune organs?
CORRECT ANSWER : Thymus
Bone Marrow These are where differentiation, proliferation, and maturation of stem cells occurs to turn them into immune cells