NPLEX 1 EXAM QUESTIONS AND

NPLEX 1 EXAM QUESTIONS AND

ANSWERS 100% SOLVED (Newest 2025) what co-factor is required to convert dUMP to DTMP via thymidylate synthase? - Correct Answers ✅methylene-FH4 what cofactor is needed for homocysteine-->methionine conversion? - Correct Answers ✅methylcobalamin (B12) where are arthersclerotic plaques formed? - Correct Answers ✅subintimal space or tunica intima cholesterol is primarily carried by what lipoprotein? - Correct Answers ✅LDL What apoproteins are on the surface of VLDL? - Correct Answers ✅Apoproteins B-100, C-II, and E what apoproteins are on the surface of HDL? - Correct Answers ✅Apoprotein A-I, C-II, and E Why are HDLs considered "good" cholesterol? - Correct Answers ✅they are considered a "reverse cholesterol transporter" they transport cholesterol to the liver for disposal or to other tissues for use by converting cholesterol to a cholesterolester

(CE). 1 / 4

NPLEX 1 EXAM QUESTIONS AND

ANSWERS 100% SOLVED (Newest 2025) apoA1 activates LCAT (lecithin cholesterol acyl transferase) to attach a fatty acyl group to cholesterol to form the CE. the CE then gets recycled in the liver what amino acids make up glutathione? - Correct Answers ✅glutamate, cysteine**, glycine ** contains the -SH (thiol) group what enzyme needs selenium as a cofactor? - Correct Answers ✅glutathione peroxidase what two reactants, enzyme, and cofactor are required to

form cystathionine? - Correct Answers ✅reactants: (1)

serine (2) homocysteine

enzyme: cystathionine synthase

cofactor: PLP (pyridoxine, B6)

why do we care about cystathionine? - Correct Answers ✅gets converted to cysteine which is a major component of GLUTATHIONE, our body's major antioxidant what cofactor is required to convert cystathionine to cysteine? - Correct Answers ✅PLP 2 / 4

NPLEX 1 EXAM QUESTIONS AND

ANSWERS 100% SOLVED (Newest 2025)

which lipid composition should be higher at 35wk gestation:

sphingomyelin or phosphatidylcholine? - Correct Answers ✅phosphatidylcholine!how many SAMs are needed to make phosphatidylcholine? - Correct Answers ✅3 SAM reactions what is the general structure of a phospholipid? how would

phosphatidylcholine look? - Correct Answers ✅General:

(1) glycerol back bone (2) FA groups (1) phosphate -- (1) head group** ** head group gives it the different functions!phosphatidylcholine has a CHOLINE head group what damage does homocysteine cause that leads to an increase risk in CV disease? - Correct Answers ✅endothelial cell damage function of VLDL - Correct Answers ✅transports triglycerides produced in the liver to extrahepatic tissues such as adipose and muscle (aka removal of TG from the liver) 3 / 4

NPLEX 1 EXAM QUESTIONS AND

ANSWERS 100% SOLVED (Newest 2025)

dietary cholesterol is transported to the liver as: - Correct

Answers ✅chylomicrons what enzyme releases FA from the membrane phospholipids?

• Correct Answers ✅phospholipase A2 (this is inhibited by

glucocorticoids*) what enzyme converts the FA into prostaglandins? - Correct Answers ✅cyclo-oxygenase 1/2 (this is inhibited by aspirin & NSAIDs*) What does phospholipase C do? - Correct Answers ✅cleaves PIP2 into IP3 and DAG what CN is involved in the motor function of the tongue - Correct Answers ✅CN XII (hypoglossal) Strep. pyogenes is common culprit of what 2 disease - Correct Answers ✅- scarlet fever

• necrotizing fasciitis

EPEC vs ETEC vs EHEC - Correct Answers ✅EPEC = NON- BLOODY self-limiting diarrhea

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