2024 CPPS 303 - Lipid Metabolism 1 New Questions and Answers ( Included ) 100% Correct
- What leads to the development of metabolic diseases?
Answer: Dietary lipid over- loads
- How are triacylgycerols digested?
Answer: Lipases: lingual, gastric, pancreatic lipase
- What are the digestion products of triacylglycerol?
Answer: fatty acids and monoacyl glyvcerols
- How does the update of triacylglycerol occur?
Answer: Passive diffusion (concentration gradient) and Facilitated transport (CD36, fatty acid transport protein 4 [FATP4])
- Where do triacylglycerol get trafficked to?
Answer: Endoplasmic reticulum
- What happens to tracylglycerol at the ER
Answer: Re-esterfication
- What happens when triacylgycerol is re-esterfied at the ER?
Answer: Formation of lipid droplets in ER membrane
- What are the two fates of lipid droplets?
Answer:
Go to the ER lumnen and become chylomicron Go to cytsol and bcome cytoplasmic lipid droplet (CLD)
- What are the metabolic fates of triacylglycerol?
Answer:
Chylomicron synthesis and secretion Beta-oxidation in mitochondria (energy generation) CLD storage synthesis of other complex lipids (phospholipids)
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