2024 CPPS 303 - Female Reproduction New Full Questions and Answers ( Included ) 100% Correct
- What does the ovary consist of?
Answer: Inner medulla and an outer zone called a cortex that surrounds the medulla except at the hilus
- What does the cortex of the ovary of a mature female contain?
Answer: Developing follicles and corpus luteum at various stages of development
- What is the medulla comprised of?
Answer: large blood vessels and other stromal elements or supporting tissue
- What are the stages of maturation of follicles?
Answer:
Primary oocyte Primordial follicle Primary follicle Secondary follicle Early tertiary follicle graafian follicle ovulated ovum
- When do levels of both LH and FSH peak in the female
Answer: during fetal life, and again during early infancy, before falling to low levels throughout the rest of childhood
- What happens to LH and FSH at the onset of puberty?
Answer: They slowly rise then begin to oscillate at regular monthly levels
- During puberty, GnRH secretion becomes?
Answer: pulsatile, and the sensitivity of the gonadotrophs to feedback inhibition by estrogens decreases.
- In childhood what is sufficient to fully suppress gonadotropin output?
Answer: very low estrogen levels
- In adolescence what is required to fully suppress gonadotropin output?
Answer: - higher levels of estrogen
- In an adult woman, what is required to fully suppress gonadotropin re- lease?
Answer: very high levels of estrogen
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- During maturation, the sensitivity of the hypothalamic-pituitary system to
inhibition by sex steroids to reach the low level that is characteristic of the adult
Answer: fall
- GnRH is released in bursts into portal vessels about per hour?
Answer: Once
- What does the hourly release of GnRH produce?
Answer: hourly surges in release of the gonadotropins LH and FSH
- In early follicular phase of the cycle, when gonadotrophs are not very GnRH
sensitive what does the GnRH cause in regards to LH
Answer: A small rise in LH
- In later stages of the follicular phase, when the gonadotrophs in the anterior
pituitary become more sensitive to GnRH what does the GnRH trig- ger?
Answer: Much larger release of LH
- What happens if pulses of GnRH are spaced 60-90 minutes apart?
Answer: Up- regulate the gonadotrophs' GnRH receptors and thus stimulate the
release of gondaotropins.
- What happens if there is continuous administration of GnRH
Answer: Downregulation of the gonadotrophs' GnRH Receptors, thus suppressing
gonadotropin release and gonadal function
- What drives the menstrual cycle?
Answer: hypothalamic-pituitary-ovarian axis
- What peptides can the ovaries produce?
Answer: Inhibins and activins
- What do ovarian steroids and peptides exert?
Answer: Negative and positive feed- back on both the hypothalamus and the anterior pituitary
- The cyclic changes in ovarian steroid secretion produces changes in?
Answer: The endometriumn that are responsible for menstrual rhythm
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