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NAPSRX EXAM QUESTION S AND
ANSWERS GRADED A+
Question: what does a STAT order mean?
Correct answer: a drug needed immediately and given
only once
Question: what information does the overdosage section
of the labeling provide?
Correct answer: signs, symptoms and treatment of acute
overdoses
Question: types of drug-drug interactions:
Correct answer: duplication, opposition (antagonism) and
alteration (p.51)
Question: tolerance vs resistance
Correct answer: tolerance is the diminished response to a
drug; resistance is the cells ability to resist the effects of the drug on them.
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Question: abbreviated new drug application (ANDA)
Correct answer: the process by which applicants must
scientifically demonstrate to the FDA that their generic product is bioequivalent to or performs in the same way as the innovator drug, no duplicate testing (p. 75)
Question: the Hatch-Waxman Act of 1984
Correct answer: -A.K.A. Drug Price Competition and
Patent Restoration Act-made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability studies in order to approve an ANDA.- gave protection to the research based manufacturers by providing a 30-month automatic cooling off period once an ANDA is challenged for patent infringement (p. 75)
Question: four basic transport mechanisms
Correct answer: passive diffusion, facilitated diffusion,
active transport, and pinocytosis (p. 95)
Question: potency vs efficacy
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Correct answer: potency: amount of drug necessary to
produce desired effectefficacy: magnitude of maximal
response that can be received from a drug (p. 106)
Question: the four phases of clinical trials
Correct answer: phases I-IV (P. 124-126)
Question: Key Parts Of A Clinical Paper (5)
Correct answer: Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
Question: reliability vs validity
Correct answer: reliability = consistency and validity =
accuracy(p. 138; 143)
Question: sampling error vs selection bias
Correct answer: sampling error is unbiased and is
randomly chosen from the population. selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
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Question: independent vs dependent variable
Correct answer: An independent variable is the one that
influences the variation. A dependent variable is the variable being tested and measured in a scientific experiment (the result of applying the independent variable).
Question: Drug Utilization Review (DUR) programs
Correct answer: -involve retrospective monitoring of
physicians' prescribing patterns-more than 90% of HMOs require DURs-nowadays mostly monitors cost savings (p.181)
Question: opportunity cost
Correct answer: based on the premise that all resources
are scarce, and therefore every time we choose to use a resource it reduces the possibility of it being used in another way.