- | Page
NAPSRX CNPR EXAM (REVISED 18TH
EDITION) QUESTIONS WITH
DETAILED VERIFIED AN SWERS (100%
CORRECT ANSWERS) /AL READY
GRADED A+
Question : what does a STAT order mean?
Correct answer: a drug needed immediately and given only
once
Question : what information does the overdosage section of
the labeling provide?
Correct answer: signs, symptoms and treatment of acute
overdoses
Question : types of drug-drug interactions:
Correct answer: duplication, opposition (antagonism) and
alteration (p.51)
Question : tolerance vs resistance
- | Page
Correct answer: tolerance is the diminished response to a
drug; resistance is the cells ability to resist the effects of the drug on them.
Question : abbreviated new drug application (ANDA)
Correct answer: the process by which applicants must
scientifically demonstrate to the FDA that their generic product is bioequivalent to or performs in the same way as the innovator drug, no duplicate testing (p. 75)
Question : the Hatch-Waxman Act of 1984
Correct answer: -A.K.A. Drug Price Competition and Patent
Restoration Act -made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability studies in order to approve an ANDA.-gave protection to the research based manufacturers by providing a 30-month automatic cooling off period once an ANDA is challenged for patent infringement (p. 75)
Question : four basic transport mechanisms
- | Page
Correct answer: passive diffusion, facilitated diffusion, active
transport, and pinocytosis (p. 95)
Question : potency vs efficacy
Correct answer: potency: amount of drug necessary to produce desired effect
efficacy: magnitude of maximal response that can be received
from a drug efficacy is almost always more important that potency (p.106)
Question : the four phases of clinical trials
Correct answer: phases I-IV (P. 124-126)
Question : Key Parts Of A Clinical Paper (5)
Correct answer: Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
Question : reliability vs validity
- | Page
Correct answer: reliability = consistency and validity =
accuracy (p. 138; 143)
Question : sampling error vs selection bias
Correct answer: sampling error is unbiased and is randomly
chosen from the population.selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
Question : independent vs dependent variable
Correct answer: An independent variable is the one that
influences the variation. A dependent variable is the variable being tested and measured in a scientific experiment (the result of applying the independent variable).
Question : Drug Utilization Review (DUR) programs
Correct answer: -involve retrospective monitoring of
physicians' prescribing patterns -more than 90% of HMOs require DURs