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NAPSRX CNPR EXAM |160
QUESTIONS WITH 100% CORRECT
ANSWERS (REVISED 18TH
EDITION) |VERIFIED | UPDATED
Question 1: What does a STAT order mean?
CORRECT ANSWER: a drug needed immediately and
given only once
Question 2: What information does the overdosage
section of the labeling provide?
CORRECT ANSWER: signs, symptoms and treatment
of acute overdoses
Question 3: Types of drug-drug interactions:
CORRECT ANSWER: duplication, opposition
(antagonism) and alteration (p.51)
Question 4: Tolerance vs resistance
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CORRECT ANSWER: tolerance is the diminished
response to a drug; resistance is the cells ability to resist the effects of the drug on them.
Question 5: Abbreviated new drug application (ANDA)
CORRECT ANSWER: the process by which applicants
must scientifically demonstrate to the FDA that their generic product is bioequivalent to or performs in the same way as the innovator drug, no duplicate testing (p.75)
Question 6: The Hatch-Waxman Act of 1984
CORRECT ANSWER: -A.K.A. Drug Price Competition
and Patent Restoration Act -made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability studies in order to approve an ANDA. -gave protection to the research based manufacturers by providing a 30-month automatic cooling off period once an ANDA is challenged for patent infringement (p. 75)
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Question 7: Four basic transport mechanisms
CORRECT ANSWER: passive diffusion, facilitated
diffusion, active transport, and pinocytosis (p. 95)
Question 8: Potency vs efficacy
CORRECT ANSWER: potency: amount of drug
necessary to produce desired effect efficacy: magnitude
of maximal response that can be received from a drug efficacy is almost always more important that potency (p.106)
Question 9: The four phases of clinical trials
CORRECT ANSWER: phases I-IV (P. 124-126)
Question 10: Key Parts Of A Clinical Paper (5)
CORRECT ANSWER: Abstract_ship, Introduction,
methods, results, discussion/conclusions (p. 128-129)
Question 11: Reliability vs validity
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CORRECT ANSWER: reliability = consistency and
validity = accuracy (p. 138; 143)
Question 12: Sampling error vs selection bias
CORRECT ANSWER: sampling error is unbiased and
is randomly chosen from the population. selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
Question 13: Independent vs dependent variable
CORRECT ANSWER: An independent variable is the
one that influences the variation. A dependent variable is the variable being tested and measured in a scientific experiment (the result of applying the independent variable).
Question 14: Drug Utilization Review (DUR) programs
CORRECT ANSWER: -involve retrospective
monitoring of physicians' prescribing patterns -more than 90% of HMOs require DURs -nowadays mostly monitors cost savings (p. 181)