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MCB4271 Final Exam, MCB4271 Test Bank, Molecular and Cell Biology, MCB4271 Questions and Answers, Advanced Biology Exam, MCB4271 Study Guide, Biology Final Exam Prep
Carbapenems are effective against 98% of bacterial strains isolated from hospitals. There is a special caution of using this antibiotic to avoid the development of resistance. - ANSWER- True
Conversion of dihydrofolate back to tetrahydrofolate is essential to keep a constant supply of which nucleotide? - ANSWER- dTTP
What is the function of dihydrofolate reductase (DHFR)? - ANSWER-converts dihydrofolate to tetrahydrofolate
Trimethroprim binds to human DHFR - ANSWER-False
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Inhibiting DNA synthesis arrests the cell cycle but does not kill cells. Hence, trimethroprim is classified as a bacteriostatic antibiotic. - ANSWER-True
Sulfanilamide is an antibiotic. - ANSWER-False
Structural differences between eukaryotic and prokaryotic machinery involved in the Central Dogma of Molecular Biology (replication, transcription, translation) allow for the development of antibiotics that specifically target microbial cells. - ANSWER-True
What is this antibiotic? i cant describe this picture lol - ANSWER-Fluorquinolone
Quinolone antibiotics target DNA gyrase and topoisomerase IV.These type II topoisomerases are also found within the human proteome. - ANSWER-False
Which of the following statements is true about rifampin? - ANSWER-It inhibits bacterial RNA polymerase.
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What is the function of sulfanilamide? - ANSWER-inhibits dihydropteroate synthase
The antibiotic structure show below is (4 six-membered rings) - ANSWER-a tetracycline
Tetracyclines bind to the 50S ribosomal subunit. - ANSWER- False
Chloramphenicol binds to 50S ribosomal subunit and inhibits peptidyl transferase - ANSWER-True
What is the function of the hydrophobic fatty acid chain in lipopeptides? - ANSWER-Allows the antibiotic to penetrate cell membrane
The majority of antibiotic classes were developed during the Golden Age of antibiotics. Since then, very few new classes were introduced into clinical use. - ANSWER-True
Hemoperfusion devices - ANSWER-Filtering blood from bacteria
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