- | Page
MB (ASCP) EXAM QUEST IONS AND
ANSWERS LATEST
Question : Which of the following is not a component of a
nucleotide?Phosphate group Anti-codon Ribose sugar Nitrogen base
Correct answer: Anti-codon
Question : According to Chargaff's rule of base pairing, adenine
pairs with:
Correct answer: Thymine
Question : What genes would be screened in a breast cancer
panel?
Correct answer: HER2, ERBB2, BRCA1
Question : Next Generation Sequencing uses:
Correct answer: Short sequence reads
- | Page
Question : Purines and pyrimidines differ from each other in
that:
Correct answer: Purines have two rings; pyrimidines have one
ring
Question : The purines are: Cytosine and uracil Adenine and thymine Thymine and cytosine Adenine and guanine
Correct answer: Adenine and guanine
Question : What is the rate of mutation per round of DNA
replication?
- in 1,000 base pairs
- in 10,000 base pairs
- in 1,000,000 base pairs
- in 1,000,000,000 base pairs
Correct answer: 1 in 1,000,000,000 base pairs
- | Page
Question : The rate of DNA migration through an agarose gel
during electrophoresis does not depend on which of the following factors?Net charge of the molecule Size of the molecule Shape of the molecule Nucleotide sequence of the molecule
Correct answer: Nucleotide sequence of the molecule
Question : What are the phases in a qPCR Amplification Plot?
Initiation, exponential, plateau Baseline, exponential, plateau Baseline, threshold, exponential, plateau Baseline, initiation, threshold, exponential, plateau
Correct answer: Initiation, exponential, plateau
Question : Find the palindrome in this restriction enzyme site:
5'-CTGCAG-3'?
5'-GAC
3'-GAC
3'-CTG
- | Page
5'-GTC
Correct answer: 3'-GAC
Question : A patient with impaired judgment, personality
changes, signs of abnormal body movements and depression comes to the physician's office for a follow-up visit. The physician suspects a single-gene disorder may be the cause of those clinical manifestations. A blood specimen was then sent to your clinical laboratory for mutation screening in the Huntington gene. Testing with standard PCR indicates that patient has Huntington Disease, HD. Which of the following would be consistent with this diagnosis?25 CAG repeats in the Huntington gene 85 CAG repeats in the Huntington gene 25 CGA repeats in the Huntington gene 85 CGA repeats in the Huntington gene
Correct answer: 85 CAG repeats in the Huntington gene
Question : Which two HPV types are responsible for most cases
of cervical cancer?16 and 18 31 and 59