BIOD322 / BIOD 322 Module 2 (Latest Update 2025 / 2026) Neuroscience | Questions & Answers | Grade A | 100% Correct - Portage Learning
Neural Function and Transmission
Question:
Docking of synaptic vesicles packaged with small molecule neurotransmitters occurs through the interaction of three membrane-bound proteins called what?
Answer:
SNARE proteins
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Question:
What are the three SNARE proteins?
Answer:
synaptobrevin, syntaxin, and SNAP-25
Question:
Which SNARE protein is called v-SNARE becuase it is located on the vesicular membrane?
Answer:
Synaptobrevin
Question:
Which SNARE proteins are called t-SNAREs because they are located on terminal membrane?
Answer:
Syntaxin and SNAP-25
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Question:
The influx of calcium through the voltage-gated calcium channels initiates the exocytosis process which leads to?
Answer:
Neurotransmitter release
Question:
Calcium enters the cell and interacts with a vesicle-bound protein called what? What does this protein do?
Answer:
Synaptotagim | Synaptotagmin is a calcium sensor that detects elevated levels of calcium in the axon terminal
Question:
Full-fusion vs. kiss-and-run exocytosis
Answer:
Full fusion - fully incorporates itself or fuses with the terminal membrane, releasing all enclosed neurotransmitter into synaptic terminal Kiss and run - temporarily fuses with the membrane and partially releases some neurotransmitter into synaptic terminal
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Question:
Ionotropic (Ligand-gated)
Answer:
Ionotropic - transmembrane proteins with pores that open in response to binding of a ligand (neurotransmitter), opening permits ions to rush into post-synaptic neuron and elicit a direct response
Question:
Metabotropic (G protein coupled) receptors, also called seven- transmembrane receptors or 7-TM receptors
Answer:
Metabotropic - membrane bound receptor complex that causes the cell to change its metabolism that leads to excitation or inhibition of postsynaptic cell, G protein (along with signaling molecules) itself will causes a change in the cell, not an ion
Question:
G protein coupled receptors bind to what? (2)
Answer:
GTP and GDP
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