NR-565 Advanced Pharmacology Fundamentals
Final Study Guide
What are the treatments for GERD?
Correct Answer:
H2 Blockers, PPIs and Antacids
What drug promotes ulcer healing by creating a protective barrier against acid and pepsin?
Correct Answer:
Sucralfate (Antacids) 60-90% for 4-6 weeks, 1 hour before of 2 hours after a meal; use to prevent and treat duodenal ulcers.
Lifestyle modifications to support ulcer healing:
Correct Answer:
Stop smoking, change in eating pattern (smaller meals and avoiding caffeine), avoid aspirin and NSAIDs, stop alcohol consumption, decrease stress and anxiety.
Who can safely receive the Hepatitis B vaccine?
Correct Answer:
Birth and up (expect soreness at injection site and mild to moderate fever). 1 / 3
Hepatitis B virus (HBV) vaccine Contraindications:
Correct Answer:
Soreness at injection site and mild to moderate fever. Prior anaphylactic reaction to the vaccine itself or baker's yeast.
What is the Rabies vaccine schedule?
Correct Answer:
The first dose ASAP after exposure, then 3,7,14 days later
Thyroid crisis treatment:
Correct Answer:
High doses of potassium iodide or strong iodine solution are given to suppress thyroid hormone release.
Methimazole
Correct Answer:
Given to suppress thyroid hormone synthesis.
Results of not treating hypothyroidism during pregnancy
Correct Answer:
Can result in permanent neuropsychological deficits in the child - decrease child's IQ
- / 3
Hypothyroidism in pregnancy
Correct Answer:
Currently recommend routine screening for hypothyroidism as soon as pregnancy is confirmed; Women already taking thyroid hormone replacement will need to increase dose by 50% max between weeks 4 -8 of gestation and the levels will level out by week 16;
Methimazole
Correct Answer:
First line drug of choice (not given to women who are pregnant or breastfeeding)
Blocks synthesis of thyroid hormone. 1) Prevents the oxidation of iodine, therefore inhibiting incorporation of iodine into tyrosine. 2) prevents iodinated tyrosine from coupling
Propylthiouracil
Correct Answer:
Preferred treatment for thyroid storm
Beta blockers
Correct Answer:
Help with tachycardia experienced with hyperthyroidism, can mask hypoglycemia.
- / 3