NR-507 Advanced Pathophysiology
Final Exam
The Monoamine Deficiency Theory states that the underlying basis of depression is low levels of serotonin, norepinephrine and dopamine.
Correct Answer:
true
Dysthymia is a persistent depressive disorder used to describe milder symptoms of depression that happen over longer periods of time.
Correct Answer:
true
Despite the different classifications, all antidepressant medications are equally effective in reducing the major symptoms of major depressive disorder.
Correct Answer:
true
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Selective Serotonin Reuptake Inhibitors are the most common antidepressants prescribed.
Correct Answer:
true
Electroconvulsive Therapy (ECT) is no longer used as a treatment of major depressive disorder (MDD).
Correct Answer:
false (Still used)
Post-partum depression
Correct Answer:
after childbirth, a mother's depressed mood (hormonal change accompanies)
atypical depression
Correct Answer:
improved mood when exposed to pleasurable or positive events
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A 42-year-old female presents to the primary care clinic with a three- month history of "feeling low", poor energy, inability to concentrate and irritability.She is concerned about her loss of interest in her usual social activities of walking with her friends and participating in her sewing group. She is especially concerned about her recent 15-pound weight gain. Other reported symptoms are frequent headaches, difficulty getting out of bed in the morning, and feeling worthless. She denies suicide ideation. She reports a family history of depression (mother and sister) and denies any consumption of drugs and alcohol. She is divorced and has a grown son who lives approximately one hour away but rarely sees because of his work schedule.The patient is interested in knowing if her symptoms are related to depression.Upon initial evaluation, the NP considers if the patient meets the criteria for MDD by consulting the DS
Correct Answer:
Depressed mood Fatigue/loss of energy Loss of interest/Anhedonia Feeling worthless or having excessive guilt Insomnia or hypersomnia Poor concentration Recurrent thoughts of death, suicide, a suicide plan or attempt Psychomotor agitation or retardation
A strong social network has been proven to lead to a better outcome for individuals with MDD.
Correct Answer:
true
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Amitriptyline (Elavil) is an alpha-agonist that increases synaptic concentration of serotonin and/or norepinephrine.
Correct Answer:
false (Amitriptyline is a tricyclic anti-depressant)
Which of the following symptoms would prompt the NP to refer the patient to a psychiatrist?
Correct Answer:
Psychotic symptoms.Suicide ideation.Patient's request.
Selective Serotonin Reuptake Inhibitors (SSRIs) block the reabsorption or inhibits the reuptake of serotonin that allows for more of it in the synaptic cleft.
Correct Answer:
true
Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) drugs increase levels of serotonin and norepinephrine in the brain by promoting their reuptake by nerves.
Correct Answer:
false (SNRIs block or delay serotonin and norepinephrine in the brain)
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