CPIA - ARENA IACUC Guidebook: CPIA
Exam Study Guide
Which of the following is an acceptable method of euthanasia?
- Decompression
- Carbon Dioxide
- Chloral Hydrate, Chloroform, and Cyanide
- Dry-Ice Generated CO2
- Neuromuscular Blockers
(Ans- B. Carbon Dioxide
The following methods of euthanasia are all UNACCEPTABLE:
- Decompression
- Chloral Hydrate, Chloroform, Cyanide
- Neuromuscular Blockers
- Dry Ice Generated CO2
ARENA IACUC Guidebook, pg. 102
Which of the 3 Rs uses a species lower on the phylogenetic scale.
- Reduction
- Refinement
- Replacement
(Ans- C. Replacement
ARENA IACUC Guidebook, pg. 97
Which of the following describes a complete loss of sensitivity to pain?
- Sedation
- Anesthesia
- Analgesia
- Tranquilization (Ans- C. Analgesia 1 / 3
ARENA IACUC Guidebook, pg. 112
Define Moribund (Ans- Moribund has been defined as "in the state of dying" or "at the point of death".
ARENA IACUC Guidebook, pg. 104
True or False: Use of death as an endpoint must be justified in writing in
proposals and its use must be approved by the IACUC prior to beginning a study. (Ans- True
ARENA IACUC Guidebook, pg. 107
Which regulatory entities mandate the IACUC to review protocols to ensure that pain and distress are minimized in laboratory animals?(Ans- Both the PHS Policy and the ARWs, in addition to being reiterated in the Guide.
ARENA IACUC Guidebook, pg. 109
Which of the following describes a total loss of sensation in a part or in the entire body?
- Sedation
- Anesthesia
- Analgesia
- Tranquilization
(Ans- B. Anesthesia
ARENA IACUC Guidebook, pg. 112
Which of the following describes a state characterized by decreased awareness of surroundings, relaxation, and sleepiness? Analgesia is not present. 2 / 3
- Sedation
- Anesthesia
- Analgesia
- Tranquilization
(Ans- A. Sedation
ARENA IACUC Guidebook, pg. 112
Which of the following describes a state of mental calmness, decreased response to environmental stimuli, and muscle relaxation? No sleep, analgesia, or anesthesia is present, even at increased dosage.
- Sedation
- Anesthesia
- Analgesia
- Tranquilization
(Ans- D. Tranquilization
ARENA IACUC Guidebook, pg. 112
Define Distress.(Ans- An aversive state in which an animal is unable to adapt completely to stressors and the resulting stress and shows maladaptive behavior.
ARENA IACUC Guidebook, pg. 112
Define Pain.(Ans- An unpleasant sensory or emotional experience associated with actual or potential tissue damage.
ARENA IACUC Guidebook, pg. 112
Which regulatory agency requires that investigators proposing procedures that may cause more than momentary or slight pain or distress to the animals will consult with the AV or his/her designee?(Ans- AWRs
- / 3