CMN 548 UNIT 5 FINAL EXAM REAL
EXAM 200+ QUESTIONS AND
CORRECT ANSWER S (VERIFIED
ANSWERS) A GRADE
Question : what medications are irreversible MAOIs
(MAOA&B and MAOB MAOB)?
CORRECT ANSWER : Isocarboxazid (Marplan), Phenelzine
(Nardil), Tranylcypromine (Parnate), Selegiline Transdermal (Emasam)
Question : A single dose of irreversible MAOIs may persist in
its inhibition of MAO for how long?
CORRECT ANSWER : 2 weeks
Question : What are the most frequent adverse effects of
irreversible MAOIs?CORRECT ANSWER : MAOA&B: dizziness, drowsiness, fatigue, headache (without increased BP), hyperreflexia, & sleep disturbances
Question : Reversible MAOIs (RIMAs) Include what
medication?
CORRECT ANSWER : Maclobemide (Manerix)
Question : How long will it take to recover MAO activity
after a final dose of RIMA?
CORRECT ANSWER : 24-48 hours
Question : What are the most frequent adverse effects of
RIMAs?
CORRECT ANSWER : orthostatic hypotension, insomnia,
weight gain, edema & sexual dysfunction, insomnia tx by dividing doses, not giving after dinner, and using trazodone
Question : MAOIs are used to treat what conditions?
CORRECT ANSWER : Depression, bipolar depression,
panic disorder, social phobia, bulimia, PTSD, angina pain, atypical face pain, migraine, ADHD, idiopathic orthostatic HTN, & depression r/t brain injury
Question : Reversible MAO-A (RIMA) used to treat:
CORRECT ANSWER : MDD, dysthymic, chronic
Question : Irreversible MAOA&B used to treat:
CORRECT ANSWER : Depression, atypical MDD,
unresponsive to other antidepressants
Question : Irreversible MAO-B used to treat:
CORRECT ANSWER : MDD in adults
Question : What is the treatment for MAOI induced
orthostatic hypotension?
CORRECT ANSWER : •Avoidance of caffeine, intake of 2L
of fluid/day, addition of dietary salt, adjustment of HTN meds, support stockings •fludrocortisone 0.1-0.2mg/day for severe cases •Advise pts to get out of bed slowly
Question : How long should the Psychiatric Nurse
Practitioner wait to begin another treatment for depression
when stopping an MAOI to begin either another MAOI or an SSRI?
CORRECT ANSWER : When changing from one MAOI to
another taper and stop use of the first drug for 10-14 days before beginning the second drug
Question : How long should the PNP wait to begin an MAOI
after discontinuing a patient from fluoxetine (Prozac)?
CORRECT ANSWER : Don't use within 5 weeks of prozac
Question : Describe potential complications for using MAOIs
for patients who have Bipolar I and Schizophrenia.
CORRECT ANSWER : Induction of mania in persons in the
depressed phase of BPI & triggering psychotic decompensating in persons w/ schizophrenia
Question : What are the symptoms of a tyramine-induced
hypertensive crisis?
CORRECT ANSWER : Results from inactive GI metabolism
of dietary Tyramine due to the MAOI's Sxs: HA usually 1st
sx, severe HTN, stiff neck, diaphoresis, nausea, vomiting