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ONS Chemotherapy Biotherapy Certification(Questions And Answers)
Question 1: What are the 3 major phases of cell division?
CORRECT ANSWER : Interphase, Mitotic phase, Cytokinesis
Question 2: What are the 3 steps of interphase?
CORRECT ANSWER : First growth phase (G1), Synthesis
phase (S phase), Second growth phase (G2)
Question 3: What are the 4 phases of mitosis?
CORRECT ANSWER : Prophase, Metaphase, Anaphase,
Telophase
Question 4: What is innate immunity?
CORRECT ANSWER : Non-specific response, either: 1. Barrier (skin, mucous membranes, flora of skin/gut) 2. Cellular
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components (phagocytes, natural killer cells, granulocytes, macrophages)
Question 5: What is adaptive immunity?
CORRECT ANSWER : Follows innate immunity if
unsuccessful. Memory immunity, including: 1. Humoral
immunity (production of antibodies or immunoglobulins) 2. Cell mediated immunity (dependent upon T cells) 3. Regulatory T - cells (prevent autoimmune reactions and limit inflammatory responses)
Question 6: Define mutations
CORRECT ANSWER : Variations in the nucleotide sequence of
a gene
Question 7: What are the 3 main goals of treatment?
CORRECT ANSWER : Cure, Control, Palliation
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Question 8: Define neoadjuvant therapy
CORRECT ANSWER : Treatment is given prior to surgery to
shrink the tumor
Question 9: Define adjuvant therapy
CORRECT ANSWER : Additional cancer treatment given after
the primary treatment to lower the risk that the cancer reoccur
Question 10: Define conditioning/preparative therapy
CORRECT ANSWER : Treatments used to prepare a patient for
stem cell transplantation
Question 11: What are the 2 types of conditioning therapies?
CORRECT ANSWER : Myeloablative, Nonmyeloablative
Question 12: Define dose density
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CORRECT ANSWER : Drug dose per unit of time
Question 13: Define dose intensity
CORRECT ANSWER : Amount of drug delivered over time
Question 14: How is relative dose intensity (RDI) calculated?
CORRECT ANSWER : By comparing the dose that the patient
ACTUALLY received to the planned dose of the standard regimen
Question 15: How do alkylating agents work?
CORRECT ANSWER : By causing a break in the DNA helix
strand, interfering with DNA replication and causing cell death