BLOOD BANK ASCP EXAM

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BLOOD BANK ASCP EXAM

QUESTIONS & ANSWERS

Question: What type of serological testing does the blood

bank technologist perform when determining the blood group of a patient?

CORRECT ANSWER : phenotyping

Question: If anti-K reacts 3+ with a donor cell with a

genotype KK and 2+ with a Kk cell, the antibody is

demonstrating:

CORRECT ANSWER : Dosage

Question: What factor(s) may account for the absence of

Fya, Fyb, and Xga antigens in James, given that Carla expresses these antigens?

CORRECT ANSWER : Gender and Race. The frequency

of Duffy antigens Fya and Fyb varies with race. The Fy(a−b−) phenotype occurs in almost 70% of African Americans and is very rare in whites. The Xga antigen is X-linked and, therefore, expressed more frequently in

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women (who may inherit the antigen from either parent) than in men.

Question: Which of the following statements is true?

• An individual with the BO genotype is homozygous

for B antigen

• An individual with the BB genotype is homozygous

for B antigen

• An individual with the OO genotype is heterozygous

for O antigen

• An individual with the AB phenotype is homozygous

for A and B antigens

CORRECT ANSWER : B. An individual with the BB

genotype is homozygous for B antigen

Question: Which genotype is heterozygous for C?

• DCe/dce

B. DCE/DCE

• Dce/dce
• DCE/dCe

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CORRECT ANSWER : A. DCe/dce

Question: Which genotype(s) will give rise to the

Bombay phenotype?

CORRECT ANSWER : The Bombay phenotype will be

expressed only when no H substance is present. The Oh type is expressed by the genotype hh. Bombays produce naturally occurring anti-H, and their serum agglutinates group O red cells in addition to red cells from groups A, B, and AB persons.

Question: Meiosis in cell division is limited to the ova

and sperm producing four gametes containing what complement of DNA?

CORRECT ANSWER: 1N. Meiosis involves two nuclear

divisions in succession resulting in four gametocytes each containing half the number of chromosomes found in somatic cells or 1N.

Question: A cell that is not actively dividing is said to be

in:

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CORRECT ANSWER : Interphase, The cell is engaged in

metabolic activity. Chromosomes are not clearly discerned; however, nucleoli may be visible

Question: Which of the following describes the

expression of most blood group antigens?

CORRECT ANSWER : Codominant

Question: What blood type is not possible for an offspring

of an AO and BO mating?

CORRECT ANSWER : All are possible

Question: The alleged father of a child in a disputed case

of paternity is blood group AB. The mother is group O and the child is group O. What type of exclusion is this?

CORRECT ANSWER : Indirect/secondary/second order.

An indirect/secondary/second order exclusion occurs when a genetic marker is absent in the child but should have been transmitted by the alleged father. In this case, either A or B should be present in the child.