Biochemistry Final Exam UNE CHEM 1005 Latest Update 2025-2026 150 Questions and 100% Verified Correct Answers Guaranteed A+
75% of amino acids liberated by degradation are... - CORRECT ANSWER: reutilized
ABC transporters - CORRECT ANSWER: assist in the transport of cholesterol and lipid from the cells to HDL
ABCG1/ABCA1 Transporter - CORRECT ANSWER: on the cell surface and is
responsible for active transport of cholesterol and lipids out of the cell into the HDL particle
Abetalipoproteinemia - CORRECT ANSWER: Loss of the ability to form lipoproteins
containing ApoB --> leads to loss of chylomicrons and VLDL
ACAT - CORRECT ANSWER: Acyl-coenzyme A acetyltransferase
Esterifies cholesterol within the cell
Acetyl-CoA is the source of... - CORRECT ANSWER: all carbons in cholesterol
synthesis
Allopurinol - CORRECT ANSWER: Inhibits xanthine oxidase
ApoCII - CORRECT ANSWER: Interacts with LPL (lipoprotein lipase) to activate the enzyme
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*Transferred to chylomicrons and VLDL from HDL particles
ApoCII on Chylomicrons and on VLDLs interact with... - CORRECT ANSWER:
Lipoprotein lipase (LPL)
-this hydrolyzes TAGs into FFAs -FFA are taken up by muscle (directly oxidized) or adipose (stored as TAGs) -insulin enhances the activity of LPL
ApoE - CORRECT ANSWER: Apoprotein on chylomicrons and VLDL used for uptake by
the liver
*Transferred to chylomicrons and VLDL from HDL particles
ApoE on chylomicron remnants... - CORRECT ANSWER: facilitates uptake by the liver SR-B1 receptor --> broken down into C, AA, and glycerol
ATP Mediated Protein Degradation - CORRECT ANSWER: proteins with short half-lives or those that are misfolded are degraded in the cytosol. This requires ATP and ubiquitin.
Attachment of ubiquitin to protein... - CORRECT ANSWER: changes the confirmation of a protein structure, targeting it to the proteasome
B12 role in amino acid metabolism (cobalamin) - CORRECT ANSWER: -required for
remethylation of homocysteine --> methionine by methionine synthase -required for the conversion of methylmalonylCoA --> succinylCoA
B6 role in amino acid metabolism (pyridoxal phosphate) - CORRECT ANSWER: -
required for transamination reactions 2 / 3
-required for the conversion of homocysteine --> cysteine by cystathionine beta- synthase
B9 role in amino acid metabolism (folate) - CORRECT ANSWER: -folate cycle is
required to transfer a methyl group of B12 during the remethylation of homocysteine -folate is a carbon carrier
Beta Oxidation - CORRECT ANSWER: Process of generating acetyl-CoA, NADH, and
FADH2 from the oxidation of FFAs taken up by peripheral tissues (mostly liver & skel.muscle tissue).
Happens in mitochondria. Long chain FFAs cannot cross the mito membrane, so a transport system is in place.
BH4 role in amino acid metabolism (tetrahydrobiopterin) - CORRECT ANSWER: -
required for metabolism of cyclic amino acids
Branched chain amino acids - CORRECT ANSWER: isoleucine, leucine, valine
Carbamoyl Phosphate Synthetase II (CPSII) role in pyrimidine synthesis - CORRECT
ANSWER: -the regulating step synthesizing carbamoyl phosphate from glutamine +
CO2 and ATP -CPSII is activated by PRPP -inhibited by UTP -similar to the CPSI reaction in the urea cycle
CETP - CORRECT ANSWER: Cholesteryl ester transfer protein
Transfers cholesteryl ester from HDL to VLDL and transfers TG from VLDL to HDL
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