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UNE (University Of New England) Medical Biochemistry Final Exam (2 LATEST VERSIONS) Features 300 Accurate And Verified Questions Covering Metabolic Pathways, Enzymatic Function, Bioenergetics, Carbohydrate And Lipid Metabolism, Protein Structure, And Clinical Correlations. Ideal For Students In Medical, Dental, Or Health Science Programs.
VERSION 1
Fatty acid synthase is a multimeric enzyme complex. Which of the following subunits contains pantothenic acid as a cofactor?
Thioesterase Ketoacyl synthase Acyl carrier protein (ACP) Enoyl reductase - ANSWER-Acyl carrier protein (ACP)
Acetyl-CoA Carboxylase will be active when which of the following hormones is elevated?
Epinephrine 1 / 4
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Cortisol Glucagon Insulin - ANSWER-Insulin
Under conditions when glucose oxidation is elevated, the acetyl-CoA produced will allosterically activate which of the following enzymes leading to an increase in the production of oxaloacetate?
Acetyl CoA carboxylase Malate dehydrogenase Pyruvate carboxylase Citrate lyases - ANSWER-Pyruvate carboxylase
Which of the following enzymes is correctly paired with its allosteric inhibitor?
Pyruvate kinase: fructose 1,6-bisphosphate
Carnitine palmitoyltransferase I: acetyl-CoA
Pyruvate dehydrogenase complex: pyruvate
Acetyl-CoA carboxylase: palmitoyl-CoA - ANSWER-Acetyl-CoA
carboxylase: palmitoyl-CoA
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Under fasting conditions, acetyl-CoA carboxylase will be inhibited by an increase in which of the following compounds?
Fatty acyl-CoA Citrate Malonyl CoA Glucose - ANSWER-Fatty acyl-CoA
After a high carbohydrate meal, which of the following enzymes will be dephosphorylated and active?
Glycogen phosphorylase Fructose 2,6-bisphosphate Hormone-sensitive lipase Acetyl-CoA carboxylase - ANSWER-Acetyl-CoA carboxylase
A defect in the thioesterase subunit of fatty acid synthase would impair which of the following activities of the enzyme complex?
Priming of the enzyme with acetyl-CoA Liberation of CO2 from 3-ketoacyl synthase Binding of malonyl-CoA to an SH group 3 / 4
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Liberation of newly assembled palmitate from the enzyme - ANSWER- Liberation of newly assembled palmitate from the enzyme
NADPH is essential for fatty acid synthesis and can be generated by which two enzymes? (+ indicates NADPH can be produced by the enzyme; - indicates the enzyme does not produce NADPH)
Column 1: Glucose 6-phosphate dehydrogenase
Column 2: Malic enzyme
Column 3: Pyruvate dehydrogenase complex
1++- 2+-- 3--- 4-++
4 1 2
3 - ANSWER-1 (++-)
Nascent chylomicrons interact with HDL particles within circulation.Which of the following Apo proteins is obtained from HDL during this interaction?
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