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BioChem C785 - WGU - Module 3 - all questions 1.Hb (hemoglobin) binds to CO (carbon monoxide) with a higher affinity
than oxygen and stabilizes the R (relaxed) state: True
2.When hemoglobin changes from the T to the R, it has a high affinity
for oxygen: True
3.When hemoglobin changes from the R to T, it has a low affinity for oxygen-
: True
4.Cooperatively refers to: structural changes that increases the affinity
for oxy- gen in hemoglobin 5.When the oxygen concentration is high, the heme shape is planar.
When the oxygen concentration is low, the heme shape is bent shape.:
True 6.The Bohr effect is a relationship between hemoglobin's oxygen binding behavior in conjunction with the pH of the surroundings. When the pH is
low, hemoglobin has low affinity for oxygen and releases oxygen: True
7.Bohr effect is a relationship between hemoglobin's oxygen binding be- havior in conjunction with the pH of the surroundings. When the pH is
high, hemoglobin has high affinity for oxygen and binds oxygen.: True
8.Relative to the lungs, the pH in the peripheral tissues is lower, because the CO2 generated by metabolism is converted to bicarbonate, which
releases proton (H+): True 1 / 2
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9.The Bohr effect is a relationship between hemoglobin's oxygen binding behavior in conjunction with the pH of the surroundings. When
the H+ ion concentration increases, the pH of the solution decreases.:
True 10.Myoglobin stores oxygen, whereas hemoglobin transports oxygen.
Myo- globin has a higher affinity for oxygen compared to hemoglobin:
True 11.Hemoglobin is an oxygen transport protein, whereas myoglobin is an oxygen storage protein. They exhibit different binding curves when plotted on a graph with total partial pressure of the oxygen (x-axis) plotted against the percentage saturation of hemoglobin (y-axis). What pattern of binding
curves do these proteins exhibit?: Hemoglobin has a sigmoidal curve
whereas the myoglobin has a hyperbolic curve.
12.Hemoglobin and myoglobin proteins bind to molecular oxygen.However, the protein part of the hemoglobin does not bind directly to the oxygen. Instead a specific atom helps bind the oxygen -: Iron
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