APHON EXAM WITH QUESTINS AND
ANSWERS LATEST UPDATE
Question : How many people ages 0-21 are diagnosed with
cancer each year?
CORRECT ANSWER : 15,000 - 16,000
Question : What are the top 2 pediatric oncology diagnoses +
the %
CORRECT ANSWER : 1. Leukemia - 29%2. Brain / CNS -
26%
Question : What is the 5 yr survival rate for all peds onc
diagnoses?For ALL?For AML?CORRECT ANSWER : All Dx: > 80%ALL: 90%AML: 65%
Question : Natural cell death
CORRECT ANSWER : Apoptosis
Question : Cell death from an insult that leads to rupture of
the cell membrane and spilling of cell contents
CORRECT ANSWER : Necrosis
Question : Regulates normal cell growth and repair
CORRECT ANSWER : Proto-oncogenes
Question : Blood cell production
CORRECT ANSWER : Hematopoiesis
Question : Period of time when the pt's WBCs are the lowest,
from day 7-10
CORRECT ANSWER : Nadir
Question : What time is when a pt is at the greatest risk for
infection
CORRECT ANSWER : During Nadir
Question : Goal of chemo
CORRECT ANSWER : Stop cell cycle/growth from
occurring and coming back
Question : Why are multiple chemo agents used?
CORRECT ANSWER : Resistance to a single chemo agent
can occur
Question : Chemo cells OUT of bone marrow and in the
peripheral system
CORRECT ANSWER : Blasts
Question : Chemotherapy affects 4 things
CORRECT ANSWER : 1. Malignant cells2. Epidermal3.
Bone Marrow4. Epithelial lining
Question : S/S of Childhood Cancer
CORRECT ANSWER : fever, HA, n/v, fatigue, pain,
petechiae, pallor, changes in gait, pancytopenia, lymphadenopathy, night sweats, hematuria, anorexia, abdominal or extremity mass
Question : What 4 things can tumor markers monitor
CORRECT ANSWER : 1. tumor cell origin2. tumor cell
activity3. therapy response4. recurrent disease
Question : A feature or byproduct of tumor cells that is an
indication of tumor cells and its response to therapy
CORRECT ANSWER : Tumor markers
Question : Staging of tumors: TNM system CORRECT ANSWER : T: Tumor sizeN: lymph Node
involvementM: distant Metastases
Question : The study of the effect of a drug on the body
CORRECT ANSWER : Pharmacodynamics
Question : The movement of a drug in the body and studies
how the body affects the administered drug