3P Principles of Pharmacology
1. Fick's Law of Diffusion describes drug mobility as the:
Answer: passive diffusion of non-ionized drugs down a concentration gradient from an area of high concentrationto low concentration.
- Which of the following is a neurotransmitter within the parasympatheticnervous system?
Answer: Acetylcholine
- Pharmacodynamic interactions that occur when two drugs act on distinctreceptors is known
as:
Answer: heterodynamic competitors.
- Therapeutic indices of a drug should be determined from a serum sampleobtained during:
Answer: at steady state of the drug.
- The signal transduction process that carries transmitters (e.g., steroid hormones) to distant
sites via the circulatory system is known as:
Answer: endocrine.
6. Acetylcholine works at the neuromuscular junction to activate:
Answer: skeletalmuscles.
- The fusion of the synaptic vesicles to the presynaptic plasma membrane ispreceded by the
influx of:
Answer: calcium ions.
- Which of the following is considered an inhibitory neurotransmitter?
Answer: -Glycine
- The process whereby a drug's activity is altered in order to prepare it forexcretion is known
as:
Answer: biotransformation.
- The amino acid found in dairy products, fish and eggs is tyrosine. Theamino acid from
which tyrosine is made is:
Answer: phenylalanine.
- The ion that is most critical in the release of the neurotransmitter from thepresynaptic
neuron is:
Answer: calcium.
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