{"id":27559,"date":"2025-06-20T03:20:17","date_gmt":"2025-06-20T03:20:17","guid":{"rendered":"https:\/\/gaviki.com\/blog\/?p=27559"},"modified":"2025-06-20T03:20:24","modified_gmt":"2025-06-20T03:20:24","slug":"what-is-the-product-of-this-reaction-2","status":"publish","type":"post","link":"https:\/\/gaviki.com\/blog\/what-is-the-product-of-this-reaction-2\/","title":{"rendered":"What is the product of this reaction"},"content":{"rendered":"\n<p>What is the product of this reaction? (Note: NaBD4 is the same as NaBH4 where the hydrogens have been replaced by deuterium) NaBD4 H2O CH3OH OH CDCH3 OD CHCH3 OD CDCH3 CH2CO2CH3 A B CH3<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"639\" src=\"https:\/\/gaviki.com\/blog\/wp-content\/uploads\/2025\/06\/image-72.png\" alt=\"\" class=\"wp-image-27560\" srcset=\"https:\/\/gaviki.com\/blog\/wp-content\/uploads\/2025\/06\/image-72.png 1024w, https:\/\/gaviki.com\/blog\/wp-content\/uploads\/2025\/06\/image-72-300x187.png 300w, https:\/\/gaviki.com\/blog\/wp-content\/uploads\/2025\/06\/image-72-768x479.png 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-green-cyan-color\">The Correct Answer and Explanation is:<\/mark><\/strong><\/p>\n\n\n\n<p>The correct answer is <strong>D<\/strong>.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Explanation:<\/h3>\n\n\n\n<p>The starting compound is <strong>acetophenone<\/strong>, a molecule containing a phenyl group (benzene ring) attached to a carbonyl group (C=O) and a methyl group (CH\u2083). The reaction involves the use of <strong>NaBD\u2084<\/strong>, which is sodium borodeuteride. This reagent functions like NaBH\u2084 but donates <strong>deuterium (D)<\/strong> instead of hydrogen (H) during reduction.<\/p>\n\n\n\n<p>The reduction of a ketone (like acetophenone) by NaBD\u2084 occurs in two steps:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Nucleophilic attack<\/strong>: NaBD\u2084 donates a deuteride ion (D\u207b) to the carbon of the carbonyl group. This breaks the double bond and forms an alkoxide intermediate (Ph-CHD-O\u207b).<\/li>\n\n\n\n<li><strong>Protonation<\/strong>: The alkoxide is then protonated by an acid (H\u2083O\u207a), giving the corresponding alcohol.<\/li>\n<\/ol>\n\n\n\n<p>As a result, the carbonyl carbon, which was sp\u00b2 hybridized and double bonded to oxygen, becomes sp\u00b3 hybridized and bears both a hydroxyl group (OH) and a <strong>deuterium-labeled<\/strong> methyl group (CDH\u2083). The final product is <strong>1-phenylethanol<\/strong>, but with <strong>deuterium<\/strong> at the carbon that was formerly part of the carbonyl group.<\/p>\n\n\n\n<p>Now let&#8217;s analyze the options:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>A<\/strong> shows OH and CDCH\u2083: hydroxyl is present, and a deuterium is on the methyl group, not on the carbon directly attached to the OH, so <strong>incorrect<\/strong>.<\/li>\n\n\n\n<li><strong>B<\/strong> shows OD and CHCH\u2083: deuterium is incorrectly on the oxygen, not from the hydride donor, so <strong>incorrect<\/strong>.<\/li>\n\n\n\n<li><strong>C<\/strong> is an ester and does not match the starting material, so <strong>incorrect<\/strong>.<\/li>\n\n\n\n<li><strong>D<\/strong> shows OH and CDCH\u2083: hydroxyl on the former carbonyl carbon, and a deuterium also attached there, which is <strong>correct<\/strong>.<\/li>\n<\/ul>\n\n\n\n<p>Thus, <strong>D<\/strong> is the correct product of the reduction of acetophenone using NaBD\u2084 in methanol followed by acidic work-up.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"https:\/\/gaviki.com\/blog\/wp-content\/uploads\/2025\/06\/learnexams-banner5-43.jpeg\" alt=\"\" class=\"wp-image-27561\" srcset=\"https:\/\/gaviki.com\/blog\/wp-content\/uploads\/2025\/06\/learnexams-banner5-43.jpeg 1024w, https:\/\/gaviki.com\/blog\/wp-content\/uploads\/2025\/06\/learnexams-banner5-43-300x300.jpeg 300w, https:\/\/gaviki.com\/blog\/wp-content\/uploads\/2025\/06\/learnexams-banner5-43-150x150.jpeg 150w, https:\/\/gaviki.com\/blog\/wp-content\/uploads\/2025\/06\/learnexams-banner5-43-768x768.jpeg 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>What is the product of this reaction? (Note: NaBD4 is the same as NaBH4 where the hydrogens have been replaced by deuterium) NaBD4 H2O CH3OH OH CDCH3 OD CHCH3 OD CDCH3 CH2CO2CH3 A B CH3 The Correct Answer and Explanation is: The correct answer is D. Explanation: The starting compound is acetophenone, a molecule containing [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-27559","post","type-post","status-publish","format-standard","hentry","category-quiz-questions"],"_links":{"self":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts\/27559","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/comments?post=27559"}],"version-history":[{"count":1,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts\/27559\/revisions"}],"predecessor-version":[{"id":27562,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts\/27559\/revisions\/27562"}],"wp:attachment":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/media?parent=27559"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/categories?post=27559"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/tags?post=27559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}