{"id":26926,"date":"2025-06-19T19:41:42","date_gmt":"2025-06-19T19:41:42","guid":{"rendered":"https:\/\/gaviki.com\/blog\/?p=26926"},"modified":"2025-06-19T19:41:47","modified_gmt":"2025-06-19T19:41:47","slug":"in-adipose-and-skeletal-muscle-cells-insulin-stimulates","status":"publish","type":"post","link":"https:\/\/gaviki.com\/blog\/in-adipose-and-skeletal-muscle-cells-insulin-stimulates\/","title":{"rendered":"In adipose and skeletal muscle cells, insulin stimulates"},"content":{"rendered":"\n<p>In adipose and skeletal muscle cells, insulin stimulates: <\/p>\n\n\n\n<p>1) active transport of glucose <\/p>\n\n\n\n<p>2) opening of chemically-gated channels <\/p>\n\n\n\n<p>3) entry of insulin into cells <\/p>\n\n\n\n<p>4) opening of glucose channels<\/p>\n\n\n\n<p>5) increased cell membrane glucose carriers<\/p>\n\n\n\n<p><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-cyan-blue-color\"><strong>The correct answer and explanation is:<\/strong><\/mark><\/p>\n\n\n\n<p><strong>Correct Answer:<\/strong><br><strong>5) increased cell membrane glucose carriers<\/strong><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Explanation (300 words):<\/strong><\/h3>\n\n\n\n<p>Insulin plays a critical role in regulating blood glucose levels, especially after meals. In <strong>adipose (fat)<\/strong> and <strong>skeletal muscle<\/strong> cells, insulin promotes <strong>glucose uptake<\/strong> primarily by increasing the number of <strong>glucose transport proteins<\/strong> on the cell membrane.<\/p>\n\n\n\n<p>These glucose transport proteins are known as <strong>GLUT4 transporters<\/strong>. Normally, GLUT4 resides inside the cell, stored in vesicles. When insulin binds to its receptor on the surface of adipose or muscle cells, it triggers a signal transduction pathway that causes these vesicles to move to the cell membrane and fuse with it. This process increases the number of <strong>glucose carriers<\/strong> (GLUT4 proteins) on the membrane, making it easier for glucose to enter the cell from the bloodstream.<\/p>\n\n\n\n<p>The mechanism is <strong>not<\/strong> about:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>(1) Active transport of glucose<\/strong> \u2013 Glucose entry is through <strong>facilitated diffusion<\/strong>, not active transport.<\/li>\n\n\n\n<li><strong>(2) Opening of chemically-gated channels<\/strong> \u2013 These are typical for ions like Na\u207a or K\u207a, not glucose.<\/li>\n\n\n\n<li><strong>(3) Entry of insulin into cells<\/strong> \u2013 Insulin binds to surface receptors; it does not enter the cell to function.<\/li>\n\n\n\n<li><strong>(4) Opening of glucose channels<\/strong> \u2013 GLUT4 is a <strong>carrier protein<\/strong>, not a channel that opens like an ion channel.<\/li>\n<\/ul>\n\n\n\n<p>Thus, insulin <strong>does not open a &#8220;channel&#8221;<\/strong> but rather increases the number of GLUT4 <strong>carriers<\/strong>, which work via <strong>facilitated diffusion<\/strong>, a passive process that depends on glucose concentration gradients.<\/p>\n\n\n\n<p>This effect is essential in lowering blood glucose levels after meals and providing muscle and fat cells with glucose for energy production or fat synthesis. A failure in this mechanism, such as in <strong>Type 2 diabetes<\/strong>, results in poor glucose uptake despite normal or high insulin levels, often due to insulin resistance where cells fail to respond properly to insulin.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In adipose and skeletal muscle cells, insulin stimulates: 1) active transport of glucose 2) opening of chemically-gated channels 3) entry of insulin into cells 4) opening of glucose channels 5) increased cell membrane glucose carriers The correct answer and explanation is: Correct Answer:5) increased cell membrane glucose carriers Explanation (300 words): Insulin plays a critical [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-26926","post","type-post","status-publish","format-standard","hentry","category-quiz-questions"],"_links":{"self":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts\/26926","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/comments?post=26926"}],"version-history":[{"count":1,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts\/26926\/revisions"}],"predecessor-version":[{"id":26928,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts\/26926\/revisions\/26928"}],"wp:attachment":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/media?parent=26926"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/categories?post=26926"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/tags?post=26926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}