{"id":18988,"date":"2025-06-13T11:45:04","date_gmt":"2025-06-13T11:45:04","guid":{"rendered":"https:\/\/gaviki.com\/blog\/?p=18988"},"modified":"2025-06-13T11:45:09","modified_gmt":"2025-06-13T11:45:09","slug":"the-current-cdc-guidelines-also-recommend-non-replicating-adenovirus-vector-based-dna-vaccines-for-primary-and-booster-vaccination-in-all-populations","status":"publish","type":"post","link":"https:\/\/gaviki.com\/blog\/the-current-cdc-guidelines-also-recommend-non-replicating-adenovirus-vector-based-dna-vaccines-for-primary-and-booster-vaccination-in-all-populations\/","title":{"rendered":"The current CDC guidelines also recommend non-replicating adenovirus vector-based DNA vaccines for primary and booster vaccination in all populations"},"content":{"rendered":"\n<p>The current CDC guidelines also recommend non-replicating adenovirus vector-based DNA vaccines for primary and booster vaccination in all populations. (a) True (b) False<\/p>\n\n\n\n<p><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-vivid-cyan-blue-color\"><strong>The correct answer and explanation is:<\/strong><\/mark><\/p>\n\n\n\n<p><strong>Correct Answer: (b) False<\/strong><\/p>\n\n\n\n<p><strong>Explanation:<\/strong><\/p>\n\n\n\n<p>The Centers for Disease Control and Prevention (CDC) does not currently recommend non-replicating adenovirus vector-based DNA vaccines for primary and booster vaccination in all populations. Specifically, the Johnson &amp; Johnson (Janssen) COVID-19 vaccine, which utilizes a non-replicating adenovirus vector, was previously authorized for emergency use in the United States. However, due to safety concerns, including an increased risk of Guillain-Barr\u00e9 Syndrome and thrombosis with thrombocytopenia syndrome (TTS), the CDC and the Advisory Committee on Immunization Practices (ACIP) issued a clinical preference for mRNA vaccines (Pfizer-BioNTech and Moderna) over the Johnson &amp; Johnson vaccine. As of May 2023, the Johnson &amp; Johnson COVID-19 vaccine was discontinued in the U.S., and its Emergency Use Authorization (EUA) was revoked in June 2023 upon the manufacturer&#8217;s request due to reduced demand and the availability of other vaccines .(<a href=\"https:\/\/www.verywellhealth.com\/johnson-and-johnson-covid-19-vaccine-5093160?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\">verywellhealth.com<\/a>)<\/p>\n\n\n\n<p>While non-replicating adenovirus vector-based vaccines, such as the AstraZeneca (AZD1222) and Sputnik V vaccines, have been used in other countries, their use is not universally recommended. The CDC&#8217;s current recommendations prioritize mRNA vaccines for COVID-19 vaccination due to their safety profiles and effectiveness.(<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9687223\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\">pmc.ncbi.nlm.nih.gov<\/a>)<\/p>\n\n\n\n<p>Therefore, the statement that the CDC recommends non-replicating adenovirus vector-based DNA vaccines for primary and booster vaccination in all populations is false.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The current CDC guidelines also recommend non-replicating adenovirus vector-based DNA vaccines for primary and booster vaccination in all populations. (a) True (b) False The correct answer and explanation is: Correct Answer: (b) False Explanation: The Centers for Disease Control and Prevention (CDC) does not currently recommend non-replicating adenovirus vector-based DNA vaccines for primary and booster [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-18988","post","type-post","status-publish","format-standard","hentry","category-quiz-questions"],"_links":{"self":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts\/18988","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/comments?post=18988"}],"version-history":[{"count":1,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts\/18988\/revisions"}],"predecessor-version":[{"id":18989,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/posts\/18988\/revisions\/18989"}],"wp:attachment":[{"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/media?parent=18988"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/categories?post=18988"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gaviki.com\/blog\/wp-json\/wp\/v2\/tags?post=18988"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}