Spina bifida may involve all of the following, EXCEPT: – meningomyelocele – paraplegia – hydrocephalus – meningocele – multiple sclerosis

The correct answer and explanation is:

Correct Answer: Multiple sclerosis


Explanation:

Spina bifida is a type of neural tube defect that occurs during fetal development when the spinal column fails to close completely. This condition can lead to a range of neurological impairments and physical disabilities. There are several types of spina bifida, and they may involve various complications. Let’s break down each option:


Involved in Spina Bifida:

  1. Meningomyelocele:
    • This is the most severe form of spina bifida.
    • It involves a protrusion of the spinal cord and meninges (the protective membranes) through an opening in the spine.
    • It often leads to paralysis, bladder and bowel dysfunction, and other neurological impairments.
  2. Paraplegia:
    • Paraplegia refers to paralysis of the lower body, which can result from nerve damage associated with spina bifida.
    • Especially in cases like meningomyelocele, the spinal nerves may be significantly affected, leading to motor deficits.
  3. Hydrocephalus:
    • Many children with severe spina bifida (especially meningomyelocele) develop hydrocephalus.
    • This is a condition where excess cerebrospinal fluid (CSF) accumulates in the brain, requiring treatment such as a ventriculoperitoneal (VP) shunt.
  4. Meningocele:
    • A less severe form of spina bifida.
    • The meninges protrude through the spinal opening, but the spinal cord remains in place.
    • It may not cause significant neurological problems, though surgery is often done to repair the defect.

Not Involved in Spina Bifida:

  1. Multiple Sclerosis (MS):
    • MS is a chronic autoimmune disease of the central nervous system, in which the immune system attacks the myelin sheath around nerves.
    • It develops in adulthood and has no relation to congenital conditions like spina bifida.
    • Therefore, MS is not associated with spina bifida and is the correct answer to this “EXCEPT” question.

Summary: While meningomyelocele, meningocele, paraplegia, and hydrocephalus are commonly linked with spina bifida, multiple sclerosis is not—it is a completely different neurological disorder.

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