Serum creatinine is a sensitive indicator of kidney disease because it is produced at a constant rate and is excreted via healthy kidneys in the urine. Creatinine isAnswers: A-E
A a byproduct of sugar metabolism
Ba byproduct from creatine metabolism
C a byproduct from nucleotide metabolism
D produced by body to store creatine
E none of the above
The correct answer and explanation is:
The correct answer is B) a byproduct from creatine metabolism.
Creatinine is a waste product that is produced from the breakdown of creatine, a compound that plays a key role in energy production in muscles. Creatine is found in muscle tissue and is involved in the production of adenosine triphosphate (ATP), the primary energy source for muscle contractions. When creatine is used by muscles for energy, a small portion of it is converted into creatinine, which then enters the bloodstream.
Because the production of creatinine is relatively constant and is not significantly affected by diet or other factors, it serves as a reliable marker for kidney function. Healthy kidneys filter creatinine from the blood and excrete it in the urine. However, when kidney function declines, such as in kidney disease or renal failure, the kidneys are less able to clear creatinine, causing its levels in the blood to rise.
Creatinine levels are commonly used in clinical practice as an indicator of kidney function. Elevated serum creatinine levels may indicate impaired kidney function or kidney disease, as the kidneys are unable to filter out the creatinine at the usual rate. Additionally, the ratio of blood urea nitrogen (BUN) to serum creatinine is also used to help assess kidney function.
In summary, creatinine is a byproduct of creatine metabolism, and its levels in the blood are a useful indicator of kidney health, particularly for detecting conditions like chronic kidney disease. Regular monitoring of creatinine levels can help detect kidney dysfunction early and guide appropriate treatment.